Best Western

  • 120 S Interstate Dr

    Sikeston, MO 63801

    Map & Directions
  • 573-471-9700

About Best Western

Daily 24 Hours

Hotels & Travel

Hotels & Travel
More choices in Sikeston:

Motel 6 Sikeston Mo

110 S Interstate Drive Sikeston, MO


Midtowner Motel

833 E Malone Ave Sikeston, MO

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Editorial from

In Short
Since 1946, this Phoenix, Ariz.-based hotel chain has provided guests with comfortable accommodations. Its BestRequests program offers 16 of the most frequently requested services and amenities, including complimentary…


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